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> home > Products > Primary Antibodies > Signal Transduction > Goat Anti-GDE1 / MIR16 Antibody (internal region)
Goat Anti-GDE1 / MIR16 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NZC3 |
| Other Accession | 56209(mouse), 60418(rat), NP_057725.1 |
| Reactivity | Mouse, Rat |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 37718 Da |
| Gene ID | 51573 |
|---|---|
| Other Names | GDE1; glycerophosphodiester phosphodiesterase 1; 363E6.2; MIR16; RGS16-interacting membrane protein; membrane interacting protein of RGS16; membrane-interacting protein of RGS16 |
| Dilution | WB~~1:1000 E~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-SLSHTGDGKPRYD , from the internal region of the protein sequence according to NP_057725.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-GDE1 / MIR16 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GDE1 (HGNC:29644) |
|---|---|
| Function | Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity). Hydrolyzes glycerophospho-N-acylethanolamines to N- acylethanolamines in the brain and participates in bioactive N- acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N- oleoylethanolamine (an anorexic). In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl- lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity). Has little or no activity towards glycerophosphocholine (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane {ECO:0000250|UniProtKB:Q9JL55} |
| Tissue Location | Widely expressed.. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Genomic organization, characterization, and molecular 3D model of GDE1, a novel mammalian glycerophosphoinositol phosphodiesterase. Bachmann AS, Duennebier FF, Mocz G. Gene 2006 Apr 371 (1): 144-53.
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$ 423.00
Cat# AF4255a
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